From The Collaborative International Dictionary of English v.0.48 [gcide]:
itself \it*self"\ ([i^]t*s[e^]lf"), pron.
The neuter reflexive pronoun of It; as, the thing is good
in itself; it stands by itself.
[1913 Webster]
Borrowing of foreigners, in itself, makes not the
kingdom rich or poor. --Locke.
[1913 Webster] itsy-bitsy